Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Published in Nature Genetics, 2021

Recommended citation: Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J. van Roosmalen, Ana C. F. Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C. H. Cross, Nicolle J. M. Besselink, Bastiaan van der Roest, Sander Boymans, Koen C. Oost, Sippe G. de Vries, Holger Rehmann, Edwin Cuppen, Susanne M. A. Lens, Geert J. P. L. Kops, Wigard P. Kloosterman, Leon W. M. M. Terstappen, Chris P. Barnes, Andrea Sottoriva, Trevor A. Graham, Hugo J. G. Snippert. Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns. Nat Genet 53, 1187–1195 (2021). https://doi.org/10.1038/s41588-021-00891-2 https://www.nature.com/articles/s41588-021-00891-2